/* ============================================================
   GMXBUILDER Web Interface — Styles
   ============================================================ */

:root {
  --primary: #2563eb;
  --primary-hover: #1d4ed8;
  --bg: #f8fafc;
  --surface: #ffffff;
  --border: #e2e8f0;
  --text: #1e293b;
  --text-muted: #64748b;
  --success: #16a34a;
  --danger: #dc2626;
  --radius: 8px;
  --shadow: 0 1px 3px rgba(0,0,0,.08), 0 1px 2px rgba(0,0,0,.06);
}

*, *::before, *::after { box-sizing: border-box; margin: 0; padding: 0; }

.sr-only {
  position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px;
  overflow: hidden; clip: rect(0, 0, 0, 0); white-space: nowrap; border: 0;
}

body {
  font-family: -apple-system, BlinkMacSystemFont, "Segoe UI", Roboto, sans-serif;
  background: var(--bg);
  color: var(--text);
  line-height: 1.6;
}

/* Header */
.header {
  background: var(--surface);
  border-bottom: 1px solid var(--border);
  padding: 10px 32px;
  display: flex;
  align-items: center;
  gap: 16px;
  box-shadow: var(--shadow);
}
.logo { display: flex; align-items: center; gap: 10px; flex: 0 0 auto; }
.brand-logo {
  display: block;
  width: clamp(150px, 16vw, 200px);
  height: auto;
}
.release-badge {
  display: inline-block;
  background: #dc2626;
  color: #fff;
  font-size: 10px;
  font-weight: 700;
  padding: 2px 8px;
  border-radius: 3px;
  letter-spacing: 0.5px;
  vertical-align: super;
  margin-left: 2px;
}
.header-sub { color: var(--text-muted); font-size: 14px; }
.header-sub:empty { display: none; }
.header-task-id { margin-left: auto; color: #6366f1; font-size: 13px; display: inline-flex; align-items: center; gap: 6px; }
.header-task-id.hidden { display: none; }
.copy-task-id { border: 1px solid #a5b4fc; background: transparent; color: #4f46e5; border-radius: 4px; padding: 2px 7px; font: inherit; cursor: pointer; }
.copy-task-id:hover, .copy-task-id:focus-visible { background: #eef2ff; border-color: #6366f1; }
.copy-task-id-status { min-width: 42px; color: #059669; font-size: 12px; }
.viewer-unavailable {
  display: flex;
  align-items: center;
  justify-content: center;
  padding: 24px;
  color: #b45309;
  background: #fffbeb;
  border: 1px solid #f59e0b;
  text-align: center;
}

@media (max-width: 720px) {
  .header {
    padding: 10px 16px;
    align-items: flex-start;
    flex-wrap: wrap;
    gap: 6px 12px;
  }
  .brand-logo { width: 150px; }
  .header-sub { flex-basis: 100%; }
  .header-task-id { margin-left: 0; }
}

/* Container */
.container { max-width: 780px; margin: 32px auto; padding: 0 16px; }

/* Step navigation */
.steps {
  display: flex;
  gap: 0;
  background: var(--surface);
  border-radius: var(--radius);
  overflow: hidden;
  box-shadow: var(--shadow);
  margin-bottom: 24px;
}
.step {
  flex: 1;
  border: none;
  background: var(--surface);
  padding: 14px 8px;
  font-size: 13px;
  cursor: pointer;
  color: var(--text-muted);
  text-align: center;
  transition: background .15s;
  position: relative;
}
.step:not(:last-child)::after {
  content: '';
  position: absolute;
  right: 0;
  top: 25%;
  height: 50%;
  width: 1px;
  background: var(--border);
}
.step:hover { background: #f1f5f9; }
.step.active { color: var(--primary); font-weight: 600; background: #eff6ff; }
.step.done { color: var(--success); }
.step-num {
  display: block;
  font-size: 18px;
  font-weight: 700;
  margin-bottom: 2px;
}

/* Panels */
.panel { display: none; }
.panel.active { display: block; }
.panel h2 {
  font-size: 22px;
  margin-bottom: 20px;
  color: var(--text);
}

/* Upload zone */
.upload-zone {
  border: 2px dashed var(--border);
  border-radius: var(--radius);
  padding: 48px 24px;
  text-align: center;
  cursor: pointer;
  transition: border-color .15s, background .15s;
}
.upload-zone:hover, .upload-zone.dragover {
  border-color: var(--primary);
  background: #eff6ff;
}
.upload-icon { font-size: 48px; color: var(--primary); margin-bottom: 8px; }
.link-btn { border: none; background: none; color: var(--primary); cursor: pointer; font-size: inherit; text-decoration: underline; }

/* Upload info table */
.upload-info { margin-top: 16px; }
.upload-info table { width: 100%; border-collapse: collapse; }
.upload-info td { padding: 8px 12px; border-bottom: 1px solid var(--border); }
.upload-info td:first-child { font-weight: 600; color: var(--text-muted); width: 140px; }

/* Form grid */
.form-grid { display: grid; grid-template-columns: 1fr; gap: 16px; }
.field { display: flex; flex-direction: column; gap: 4px; }
.field label { font-weight: 600; font-size: 14px; }
.field input[type="text"],
.field input[type="number"],
.field select {
  padding: 10px 12px;
  border: 1px solid var(--border);
  border-radius: var(--radius);
  font-size: 14px;
  font-family: inherit;
  transition: border-color .15s;
}
.field input:focus, .field select:focus {
  outline: none;
  border-color: var(--primary);
  box-shadow: 0 0 0 3px rgba(37,99,235,.15);
}
.checkbox-field { flex-direction: row; align-items: center; gap: 8px; }
.checkbox-field input[type="checkbox"] { width: 18px; height: 18px; }
.hint { font-size: 12px; color: var(--text-muted); }

/* Buttons */
.panel-actions { display: flex; justify-content: space-between; margin-top: 24px; }
.viewer-box {
  position: relative;
  width: 100%;
  min-height: 280px;
  margin-top: 16px;
  overflow: hidden;
  border: 1px solid var(--border);
  border-radius: var(--radius);
  background: #fff;
  contain: layout paint;
  isolation: isolate;
}
.viewer-box canvas {
  position: absolute !important;
  inset: 0 !important;
  width: 100% !important;
  height: 100% !important;
  max-width: 100%;
  display: block;
}
.cg-check-row { margin-top: 18px; }
.cg-check-button { display: block; width: 100%; }
.cg-check-row .hint { display: block; min-height: 18px; margin-top: 6px; }
.stage-enabled { display: inline-flex; align-items: center; gap: 4px; font-size: 12px; }
.btn {
  padding: 10px 24px;
  border: 1px solid var(--border);
  border-radius: var(--radius);
  background: var(--surface);
  font-size: 14px;
  font-family: inherit;
  cursor: pointer;
  transition: background .15s, border-color .15s;
}
.btn:hover { background: #f1f5f9; }
.btn.primary {
  background: var(--primary);
  color: #fff;
  border-color: var(--primary);
}
.btn.primary:hover { background: var(--primary-hover); }
.btn:disabled { opacity: .5; cursor: not-allowed; }

/* Progress */
.progress-section { margin-top: 24px; }
.progress-bar {
  height: 8px;
  background: var(--border);
  border-radius: 4px;
  overflow: hidden;
}
.progress-fill {
  height: 100%;
  width: 0%;
  background: var(--primary);
  transition: width .3s;
}
.progress-text { margin-top: 8px; font-size: 14px; color: var(--text-muted); }

/* Result */
.result-section { margin-top: 24px; padding: 20px; border: 1px solid var(--success); border-radius: var(--radius); background: #f0fdf4; }
.result-section h3 { color: var(--success); font-size: 18px; margin-bottom: 12px; }
.result-section table { width: 100%; border-collapse: collapse; margin-bottom: 16px; }
.result-section td { padding: 4px 8px; font-size: 14px; }

/* Task type cards */
.section-desc { margin-bottom: 20px; color: var(--text-muted); }
.task-grid { display: grid; grid-template-columns: repeat(auto-fill, minmax(220px, 1fr)); gap: 14px; }
.task-card {
  background: var(--surface);
  border: 1px solid var(--border);
  border-radius: var(--radius);
  padding: 18px 16px;
  cursor: pointer;
  transition: border-color .15s, box-shadow .15s, transform .1s;
  display: flex;
  flex-direction: column;
  gap: 8px;
  width: 100%;
  color: var(--text);
  font: inherit;
  text-align: left;
}
.task-card:hover { border-color: var(--primary); box-shadow: 0 2px 8px rgba(37,99,235,.12); transform: translateY(-1px); }
.task-card:focus-visible, .lipid-card:focus-visible,
.chain-rename:focus-visible, .smallmol-name:focus-visible,
.proc-mod-res:focus-visible { outline: 3px solid rgba(37,99,235,.35); outline-offset: 2px; }
.task-card.selected { border-color: var(--primary); box-shadow: 0 0 0 3px rgba(37,99,235,.2); background: #eff6ff; }
.task-card.disabled { opacity: .5; cursor: not-allowed; filter: grayscale(.3); }
.task-card.disabled:hover { border-color: var(--border); box-shadow: none; transform: none; }
.task-card .card-icon { font-size: 28px; }
.task-card .card-category { font-size: 11px; text-transform: uppercase; letter-spacing: .5px; color: var(--primary); font-weight: 600; }
.task-card.disabled .card-category { color: var(--text-muted); }
.task-card .card-title { font-size: 15px; font-weight: 600; }
.task-card .card-desc { font-size: 12px; color: var(--text-muted); line-height: 1.4; }
.task-card .card-badge {
  align-self: flex-start;
  font-size: 10px;
  padding: 2px 8px;
  border-radius: 10px;
  background: #fef3c7;
  color: #92400e;
  font-weight: 500;
}
.task-card.selected .card-badge { display: none; }

/* Upload info sections */
.info-section-title {
  font-size: 16px;
  margin: 20px 0 10px;
  padding-bottom: 6px;
  border-bottom: 1px solid var(--border);
}
.info-section-title:first-child { margin-top: 0; }

/* Chain sequence cards */
.chain-card {
  background: #f8fafc;
  border: 1px solid var(--border);
  border-radius: var(--radius);
  padding: 16px;
  margin-bottom: 12px;
}
.chain-card .chain-header {
  font-weight: 700;
  font-size: 14px;
  margin-bottom: 10px;
  color: var(--primary);
}
.chain-card .chain-header .chain-len {
  font-weight: 400;
  color: var(--text-muted);
  font-size: 12px;
  margin-left: 8px;
}

/* Flex-wrap sequence display — no horizontal scrolling */
.seq-flex-wrap {
  font-family: 'SF Mono', 'Cascadia Code', 'Consolas', 'Fira Code', monospace;
  font-size: 12px;
  overflow-y: auto;
  max-height: 360px;
}
.seq-flex-row {
  display: flex;
  flex-wrap: wrap;
  gap: 4px 1px;
}
.seq-group {
  margin-bottom: 4px;
}
.seq-group-num {
  font-size: 9px;
  color: var(--text-muted);
  margin-bottom: 1px;
  font-weight: 500;
}
.seq-group-tags {
  display: flex;
  gap: 1px;
}
.seq-tag {
  display: inline-block;
  width: 28px;
  height: 22px;
  line-height: 22px;
  text-align: center;
  border-radius: 3px;
  font-weight: 600;
  font-size: 11px;
}
.seq-tag.protein { background: #dbeafe; color: #1e40af; }
.seq-tag.nucleic { background: #ede9fe; color: #5b21b6; }
.seq-tag.water   { background: #dcfce7; color: #166534; }
.seq-tag.ion     { background: #fef3c7; color: #92400e; }
.seq-tag.lipid   { background: #fce7f3; color: #9d174d; }
.seq-tag.other   { background: #f1f5f9; color: var(--text-muted); }

/* Lipid picker */
.lipid-picker { position: relative; }
.lipid-picker-trigger {
  display: flex;
  flex-wrap: wrap;
  align-items: baseline;
  gap: 8px;
  width: 100%;
  padding: 10px 12px;
  border: 1px solid var(--border);
  border-radius: var(--radius);
  background: var(--surface);
  cursor: pointer;
  font-family: inherit;
  font-size: 14px;
  text-align: left;
  transition: border-color .15s;
}
.lipid-picker-trigger:hover { border-color: var(--primary); }
.lipid-picker.open .lipid-picker-trigger {
  border-color: var(--primary);
  box-shadow: 0 0 0 3px rgba(37,99,235,.15);
  border-radius: var(--radius) var(--radius) 0 0;
}
.lipid-picker-name { font-weight: 700; color: var(--primary); min-width: 52px; }
.lipid-picker-desc { flex: 1; font-size: 12px; color: var(--text-muted); min-width: 200px; overflow: hidden; text-overflow: ellipsis; white-space: nowrap; }
.lipid-picker-arrow { font-size: 10px; color: var(--text-muted); margin-left: auto; }
.lipid-picker-dropdown {
  position: fixed;
  z-index: 999;
  background: var(--surface);
  border: 1px solid var(--primary);
  border-radius: var(--radius);
  box-shadow: 0 12px 36px rgba(0,0,0,.18);
  max-height: min(480px, calc(100dvh - 16px));
  max-width: calc(100vw - 16px);
  overflow: hidden;
  display: flex;
  flex-direction: column;
}
.lipid-picker-search {
  padding: 8px;
  border-bottom: 1px solid var(--border);
}
.lipid-picker-search input {
  width: 100%;
  padding: 8px 10px;
  border: 1px solid var(--border);
  border-radius: 6px;
  font-size: 13px;
  font-family: inherit;
}
.lipid-picker-search input:focus { outline: none; border-color: var(--primary); }
.lipid-picker-list { overflow-y: auto; padding: 8px; flex: 1; }
.lipid-cat-header {
  font-size: 12px;
  font-weight: 700;
  color: var(--primary);
  padding: 8px 4px 4px;
  margin-top: 4px;
  border-top: 1px solid var(--border);
}
.lipid-cat-header:first-child { border-top: none; margin-top: 0; }
.lipid-cat-grid { display: grid; grid-template-columns: repeat(auto-fill, minmax(270px, 1fr)); gap: 6px; margin-bottom: 4px; }
.lipid-card {
  display: flex;
  gap: 10px;
  align-items: center;
  padding: 8px 10px;
  border: 1px solid var(--border);
  border-radius: 6px;
  cursor: pointer;
  transition: border-color .12s, background .12s;
  background: var(--surface);
  color: var(--text);
  width: 100%;
  font: inherit;
  text-align: left;
}
.lipid-card:hover { border-color: var(--primary); background: #eff6ff; }
.lipid-card.selected { border-color: var(--primary); background: #dbeafe; box-shadow: 0 0 0 2px rgba(37,99,235,.18); }
.lipid-card.unavailable {
  cursor: not-allowed; opacity: .58; filter: grayscale(.35); background: #f8fafc;
}
.lipid-card.unavailable:hover { border-color: var(--border); background: #f8fafc; }
.lipid-card-unavailable { margin-top: 4px; color: #b91c1c; font-size: 11px; line-height: 1.35; }
.lipid-card .lipid-card-img {
  width: 80px; height: 60px;
  flex-shrink: 0;
  border-radius: 4px;
  background: #fff;
  border: 1px solid #eee;
  display: flex; align-items: center; justify-content: center;
  overflow: hidden;
}
.lipid-card .lipid-card-img canvas { width: 80px; height: 60px; }
.lipid-card .lipid-card-info { flex: 1; min-width: 0; }
.lipid-card .lipid-card-name { font-weight: 700; font-size: 13px; }
.lipid-card .lipid-card-desc { font-size: 11px; color: var(--text-muted); line-height: 1.4; white-space: nowrap; overflow: hidden; text-overflow: ellipsis; }
.lipid-card .lipid-card-meta { display: flex; gap: 8px; margin-top: 2px; font-size: 11px; }
.lipid-card .lipid-card-tag {
  padding: 1px 6px; border-radius: 8px; font-weight: 500;
  background: #f1f5f9; color: var(--text-muted);
}
.lipid-card .lipid-card-tag.charge-pos { background: #dbeafe; color: #1e40af; }
.lipid-card .lipid-card-tag.charge-neg { background: #fce7f3; color: #9d174d; }
.lipid-card .lipid-card-tag.charge-zero { background: #f1f5f9; color: var(--text-muted); }

/* Orientation step */
.orient-method-tabs {
  display: flex; gap: 0; border-radius: var(--radius);
  overflow: hidden; border: 1px solid var(--border);
}
.orient-tab,
.cg-orient-tab {
  flex: 1; padding: 10px 16px; border: none; background: var(--surface);
  font-size: 13px; font-family: inherit; cursor: pointer;
  transition: background .15s; color: var(--text-muted);
}
.orient-tab:first-child,
.cg-orient-tab:first-child { border-right: 1px solid var(--border); }
.orient-tab.active,
.cg-orient-tab.active { background: #eff6ff; color: var(--primary); font-weight: 600; }
.orient-tab:hover:not(.active),
.cg-orient-tab:hover:not(.active) { background: #f8fafc; }
.orient-auto-result { margin-top: 8px; }
.orient-auto-result table { width: 100%; }
.orient-auto-result td { padding: 6px 10px; font-size: 13px; }
.orient-auto-result td:first-child { font-weight: 600; color: var(--text-muted); width: 100px; }
.orient-controls { display: flex; gap: 16px; margin-top: 8px; }
.orient-controls .field { flex: 1; }
.readonly-field {
  min-height: 42px; display: flex; align-items: center; padding: 9px 12px;
  border: 1px solid var(--border); border-radius: var(--radius);
  background: var(--surface); color: var(--text);
}
.slider-with-input { display: flex; align-items: center; gap: 10px; }
.slider-with-input input[type="range"] { flex: 1; min-width: 100px; }
@media (max-width: 820px) {
  .orient-controls { flex-direction: column; }
}

/* Lipid composition editor */
.lipid-composition { margin-top: 4px; }
.leaflet-section {
  border: 1px solid var(--border);
  border-radius: var(--radius);
  padding: 14px;
  margin-bottom: 10px;
  background: #fafbfc;
}
.leaflet-section h4 {
  font-size: 14px;
  margin-bottom: 10px;
  color: var(--text);
}
.lipid-mix-list { display: flex; flex-direction: column; gap: 8px; margin-bottom: 8px; }
.lipid-mix-row {
  display: flex;
  align-items: center;
  gap: 10px;
  padding: 10px 12px;
  background: var(--surface);
  border: 1px solid var(--border);
  border-radius: 6px;
}
.lipid-mix-row .mix-lipid-picker {
  flex: 1;
  min-width: 140px;
}
.lipid-mix-row .mix-lipid-trigger {
  display: flex;
  align-items: center;
  gap: 6px;
  width: 100%;
  padding: 8px 10px;
  border: 1px solid var(--border);
  border-radius: 6px;
  font-size: 13px;
  font-family: inherit;
  background: var(--surface);
  cursor: pointer;
  text-align: left;
  transition: border-color .15s;
}
.lipid-mix-row .mix-lipid-trigger:hover { border-color: var(--primary); }
.mix-lipid-trigger-name { font-weight: 700; color: var(--primary); }
.mix-lipid-trigger-cat { color: var(--text-muted); font-size: 11px; margin-left: 2px; }
.mix-lipid-trigger-arrow { margin-left: auto; font-size: 9px; color: var(--text-muted); }
.lipid-mix-row .mix-ratio {
  display: flex;
  align-items: center;
  gap: 6px;
  flex: 1;
  min-width: 120px;
}
.lipid-mix-row .mix-ratio input[type="range"] {
  flex: 1;
  accent-color: var(--primary);
}
.lipid-mix-row .mix-ratio .mix-pct {
  width: 40px;
  text-align: right;
  font-size: 13px;
  font-weight: 600;
  color: var(--primary);
}
.lipid-mix-row .mix-remove {
  border: none;
  background: none;
  color: #94a3b8;
  cursor: pointer;
  font-size: 18px;
  padding: 2px 6px;
  border-radius: 4px;
}
.lipid-mix-row .mix-remove:hover { color: var(--danger); background: #fef2f2; }
.add-lipid-btn {
  font-size: 12px !important;
  padding: 6px 14px !important;
  color: var(--primary) !important;
  border-color: var(--primary) !important;
  background: #eff6ff !important;
}
.add-lipid-btn:hover { background: #dbeafe !important; }
.mix-ratio-input {
  width: 56px !important;
  padding: 6px 8px !important;
  border: 1px solid var(--border) !important;
  border-radius: 6px !important;
  font-size: 13px !important;
  font-family: inherit !important;
  text-align: center !important;
}
.mix-ratio-input:focus { outline: none; border-color: var(--primary) !important; box-shadow: 0 0 0 2px rgba(37,99,235,.15); }

/* Lipid count table */
.lipid-count-table { margin-top: 14px; }
.lipid-count-table .count-table {
  width: 100%;
  border-collapse: collapse;
  font-size: 13px;
  background: #f8fafc;
  border-radius: var(--radius);
  overflow: hidden;
}
.lipid-count-table .count-table td,
.lipid-count-table .count-table th {
  padding: 6px 12px;
  border-bottom: 1px solid var(--border);
  text-align: left;
}
.lipid-count-table .count-table th {
  font-size: 11px;
  text-transform: uppercase;
  letter-spacing: .3px;
  color: var(--text-muted);
  background: #f1f5f9;
}
.lipid-count-table .count-summary {
  font-size: 12px;
  color: var(--text-muted);
  background: #f8fafc;
  padding: 8px 12px;
}

.asymmetry-note {
  font-size: 12px;
  color: var(--text-muted);
  margin-top: 4px;
  font-style: italic;
}

/* 3Dmol viewer */
.mol-viewer {
  width: 100%;
  height: 420px;
  border: 1px solid var(--border);
  border-radius: var(--radius);
  background: #f8fafc; border: 1px solid #e2e8f0;
  position: relative;
  overflow: hidden;
  margin-bottom: 8px;
}

/* Utility */
.hidden { display: none !important; }
.error-text { color: var(--danger); font-size: 14px; }

/* Step navigation dynamic */
.steps.dynamic { overflow-x: auto; }
.steps.dynamic .step { flex: none; min-width: 80px; }

/* Locked step */
.step.locked { opacity: .45; cursor: not-allowed; pointer-events: none; }
.step.locked .step-num::after { content: ' \1f512'; font-size: 10px; }

/* Shake animation */
@keyframes shake {
  0%, 100% { transform: translateX(0); }
  20% { transform: translateX(-4px); }
  40% { transform: translateX(4px); }
  60% { transform: translateX(-4px); }
  80% { transform: translateX(4px); }
}
.steps.shake { animation: shake .35s ease; }

/* ---- Validation errors / warnings ---- */
.validation-info { margin-bottom: 16px; }
.validation-errors, .validation-warnings {
  padding: 10px 14px; border-radius: 6px; margin-bottom: 10px;
}
.validation-errors { background: #fef2f2; border: 1px solid #fecaca; }
.validation-errors h4 { margin: 0 0 6px; }
.validation-errors ul { margin: 0; padding-left: 20px; color: #991b1b; font-size: 13px; }
.validation-errors li { margin-bottom: 2px; }
.validation-warnings { background: #fffbeb; border: 1px solid #fde68a; }
.validation-warnings h4 { margin: 0 0 6px; }
.validation-warnings ul { margin: 0; padding-left: 20px; color: #92400e; font-size: 13px; }
.validation-warnings li { margin-bottom: 2px; }
.input-check-report {
  margin-top: 10px; padding: 12px 14px; border-radius: 6px;
  background: #f0fdf4; border: 1px solid #bbf7d0; color: #166534;
  font-size: 13px;
}
.input-check-report.error { background: #fef2f2; border-color: #fecaca; color: #991b1b; }
.input-check-report h4 { margin: 0 0 6px; }
.input-check-report p { margin: 4px 0; }
.input-check-report table { margin-top: 8px; width: 100%; border-collapse: collapse; }
.input-check-report th, .input-check-report td {
  padding: 5px 8px; border: 1px solid #d1fae5; text-align: left; vertical-align: top;
}
.input-check-report.error th, .input-check-report.error td { border-color: #fecaca; }
.input-check-validation { color: #047857; }

/* ---- Chain checkboxes & rename ---- */
.chain-check {
  display: inline-flex; align-items: center; gap: 6px;
  cursor: pointer; user-select: none;
}
.chain-check input[type=checkbox] { accent-color: #6366f1; }
.chain-rename {
  display: inline-block; padding: 1px 6px; margin-left: 6px;
  border-radius: 3px; cursor: pointer; font-family: monospace;
  color: #6366f1; font-size: 13px; border: 1px solid transparent;
  background: transparent;
}
.chain-rename:hover { background: #eef2ff; border-color: #c7d2fe; }
.chain-rename-input {
  border: 1px solid #6366f1; border-radius: 3px; padding: 1px 4px;
  font-size: 13px; font-family: monospace; margin-left: 6px;
  outline: none;
}

/* ---- Small molecule cards ---- */
.smallmol-card {
  display: inline-block; margin: 4px 8px 4px 0; padding: 8px 12px;
  border: 1px solid #e2e8f0; border-radius: 6px;
  background: #f8fafc; vertical-align: top;
}
.smallmol-header { display: flex; align-items: center; gap: 8px; margin-bottom: 4px; }
.smallmol-check {
  display: inline-flex; align-items: center; gap: 4px;
  cursor: pointer; user-select: none;
}
.smallmol-check input[type=checkbox] { accent-color: #6366f1; }
.smallmol-name {
  padding: 1px 6px; border-radius: 3px; cursor: pointer;
  font-family: monospace; color: #059669; font-size: 13px;
  border: 1px solid transparent; background: transparent;
}
.smallmol-name:hover { background: #ecfdf5; border-color: #a7f3d0; }
.smallmol-rename-input {
  border: 1px solid #059669; border-radius: 3px; padding: 1px 4px;
  font-size: 13px; font-family: monospace; outline: none;
}
.smallmol-info { font-size: 12px; color: #64748b; }

/* ---- Custom Lipid Modal ---- */
.modal-overlay {
  position: fixed; inset: 0; z-index: 1000;
  background: rgba(15,23,42,0.55);
  display: flex; align-items: center; justify-content: center;
}
.modal-overlay.hidden { display: none; }
.modal-panel {
  background: #fff; border-radius: 10px;
  padding: 24px 28px; width: min(560px, calc(100vw - 32px)); max-height: 90vh;
  overflow-y: auto; box-shadow: 0 20px 60px rgba(0,0,0,0.3);
}
.modal-panel h3 { margin: 0 0 16px; font-size: 16px; }
.modal-panel:focus { outline: none; }
.modal-panel .form-grid { display: flex; flex-direction: column; gap: 10px; }
.modal-panel .field label { display: block; font-size: 12px; margin-bottom: 4px; color: #475569; }
.modal-panel .field input[type=text] {
  width: 100%; padding: 7px 10px; border: 1px solid #cbd5e1; border-radius: 5px;
  font-size: 13px; font-family: monospace;
}
.custom-lipid-result { margin-top: 16px; }
.custom-lipid-preview { display: flex; gap: 16px; align-items: flex-start; flex-wrap: wrap; }
.custom-lipid-structure {
  border: 1px solid #e2e8f0; border-radius: 6px;
  min-width: 0; max-width: 100%; background: #fafafa;
  display: flex; align-items: center; justify-content: center;
}
.custom-lipid-structure canvas { display: block; max-width: 100%; height: auto; }
.custom-lipid-props { font-size: 12px; flex: 1; }
.custom-lipid-props td { padding: 3px 6px; }
.custom-lipid-props td:first-child { color: #64748b; white-space: nowrap; }
.custom-lipid-build-status {
  margin-top: 16px; padding: 12px; border: 1px solid var(--border);
  border-radius: 6px; background: rgba(37, 99, 235, .06);
}
.custom-lipid-build-status .progress-bar {
  height: 8px; margin-bottom: 10px; overflow: hidden; border-radius: 4px;
  background: #cbd5e1;
}
#custom-lipid-build-progress {
  width: 0; height: 100%; background: #2563eb; transition: width .3s;
}
#custom-lipid-build-phase, #custom-lipid-build-message { display: block; margin-top: 5px; }
.custom-lipid-build-status.failed { border-color: #dc2626; background: rgba(220, 38, 38, .06); }
.custom-lipid-build-status.failed #custom-lipid-build-progress { background: #dc2626; }
.modal-actions { display: flex; gap: 10px; justify-content: flex-end; margin-top: 16px; }
.queue-modal-panel { width: min(520px, calc(100vw - 32px)); }
.queue-details {
  display: grid; grid-template-columns: 130px 1fr; gap: 10px 14px;
  margin: 18px 0; padding: 14px; border: 1px solid var(--border);
  border-radius: 7px; background: rgba(37, 99, 235, .04);
}
.queue-details dt { color: #64748b; font-weight: 600; }
.queue-details dd { margin: 0; }
.queue-details code { user-select: all; overflow-wrap: anywhere; }
.queue-details .btn { margin-left: 8px; padding: 3px 9px; font-size: 12px; }
.queue-acknowledge {
  display: flex; align-items: center; gap: 8px; margin-top: 14px;
  color: #334155; font-weight: 600;
}

@media (max-width: 600px) {
  .modal-overlay { align-items: flex-start; padding: 8px; }
  .modal-panel, .queue-modal-panel {
    width: 100%; max-height: calc(100dvh - 16px); padding: 18px 16px;
  }
  .custom-lipid-structure, .custom-lipid-props { width: 100%; }
  .queue-details { grid-template-columns: 1fr; gap: 4px; }
  .queue-details dd { margin-bottom: 8px; }
  .lipid-cat-grid { grid-template-columns: minmax(0, 1fr); }
  .lipid-card-meta { flex-wrap: wrap; }
  .sim-stage-header { align-items: flex-start; flex-wrap: wrap; }
  .sim-stage-toggle { flex-wrap: wrap; }
  .sim-stage-summary { flex-basis: calc(100% - 32px); text-align: left; margin-left: 32px; }
  .sim-stage-header .stage-enabled { margin: 0 14px 8px auto; }
}
/* Custom lipid option in picker */
.lipid-option-custom { border-top: 1px dashed #cbd5e1; margin-top: 4px; padding-top: 6px; color: #6366f1; font-weight: 600; }

/* ---- Structure Processing ---- */
.structproc-tabs {
  display: flex; gap: 0; border-bottom: 2px solid #e2e8f0; margin-bottom: 16px;
}
.structproc-tab {
  padding: 8px 20px; border: none; background: none;
  font-size: 13px; font-weight: 600; color: #64748b;
  cursor: pointer; border-bottom: 2px solid transparent;
  margin-bottom: -2px; transition: color .15s, border-color .15s;
}
.structproc-tab.active { color: #6366f1; border-bottom-color: #6366f1; }
.structproc-tab.detected-attention:not(.active) { color: #b45309; border-bottom-color: #f59e0b; }
.structproc-tab:hover { color: #475569; }
.structproc-tab-content.hidden { display: none; }

/* Protonation table */
.proc-table {
  width: 100%; border-collapse: collapse; font-size: 13px; margin-top: 12px;
}
.proc-table th {
  background: #f1f5f9; text-align: left; padding: 6px 10px;
  font-weight: 600; color: #475569; border-bottom: 1px solid #e2e8f0;
}
.proc-table td { padding: 5px 10px; border-bottom: 1px solid #f1f5f9; }
.proc-table tr:hover td { background: #f8fafc; }
.proc-table select { padding: 2px 4px; font-size: 12px; border: 1px solid #cbd5e1; border-radius: 3px; }

.structproc-result { margin-top: 16px; max-height: 360px; overflow-y: auto; }

/* Modification sequence view */
.proc-mod-sequence {
  display: flex; flex-wrap: wrap; gap: 2px;
  font-family: monospace; font-size: 12px;
}
.proc-mod-res {
  padding: 2px 4px; border-radius: 3px; cursor: pointer;
  border: 1px solid transparent; position: relative; user-select: none;
  background: transparent; color: inherit; font: inherit;
}
.proc-mod-res:disabled { cursor: default; }
.proc-mod-res.titratable { border-bottom: 2px solid #f59e0b; }
.proc-mod-res.modifiable { background: #dcfce7; border-color: #22c55e; }
.proc-mod-res.catalog-only { color: #94a3b8; border-color: #e2e8f0; }
.proc-mod-res.modified { background: #dbeafe; border-color: #93c5fd; }
.proc-mod-res.modified::after {
  content: '◆'; font-size: 6px; position: absolute; top: -2px; right: 1px; color: #6366f1;
}
.proc-mod-res:hover { background: #eef2ff; border-color: #c7d2fe; }
.proc-mod-res.selected { background: #6366f1; color: #fff; border-color: #6366f1; }

.proc-mod-list { margin-top: 8px; }
.proc-mod-item {
  display: inline-flex; align-items: center; gap: 8px;
  padding: 4px 10px; margin: 2px 6px 2px 0;
  background: #eef2ff; border: 1px solid #c7d2fe; border-radius: 4px;
  font-size: 12px;
}
.proc-mod-item button {
  background: none; border: none; color: #ef4444; cursor: pointer;
  font-size: 14px; line-height: 1; padding: 0 2px;
}

.proc-patch-picker {
  margin-top: 12px; padding: 12px; border: 1px solid #e2e8f0; border-radius: 6px;
  background: #f8fafc;
}
.proc-patch-picker h4 { margin: 0 0 8px; font-size: 13px; }
.proc-patch-picker.hidden { display: none; }
.proc-patch-option {
  display: inline-block; padding: 6px 10px; margin: 3px;
  border: 1px solid #cbd5e1; border-radius: 4px; cursor: pointer;
  font-size: 12px; background: #fff;
}
.proc-patch-option:hover { border-color: #6366f1; background: #eef2ff; }
.proc-patch-option .patch-name { font-weight: 600; color: #6366f1; }

/* Termini rows */
.termini-chain-row {
  display: flex; align-items: center; gap: 12px; padding: 8px 0;
  border-bottom: 1px solid #f1f5f9; flex-wrap: wrap;
}
.termini-chain-row select { padding: 3px 8px; font-size: 12px; border: 1px solid #cbd5e1; border-radius: 4px; }

/* Modification chain blocks */
.proc-mod-chain-block { margin-bottom: 8px; }
.proc-mod-chain-block h4 { font-size: 13px; }

/* ---- Ion selection cards ---- */
.ion-cols { display: flex; gap: 24px; }
.ion-col { flex: 1; }
.ion-col h4 { font-size: 14px; color: #475569; margin: 0 0 8px; padding-bottom: 4px; border-bottom: 1px solid #e2e8f0; }
.ion-card-list { min-height: 40px; }
.ion-card {
  display: flex; align-items: center; gap: 10px; padding: 6px 10px;
  margin-bottom: 4px; border: 1px solid #e2e8f0; border-radius: 5px;
  background: #fff; font-size: 13px;
}
.ion-card.selected { border-color: #6366f1; background: #eef2ff; }
.ion-card input[type=radio] { accent-color: #6366f1; }
.ion-card .ion-name { font-weight: 600; min-width: 40px; }
.ion-card .ion-charge { color: #64748b; font-size: 12px; }
.ion-card .ion-remove { margin-left: auto; background: none; border: none; color: #ef4444; cursor: pointer; font-size: 16px; }
.add-ion-btn { font-size: 12px; padding: 4px 12px; }

.ion-summary-table {
  width: 100%; border-collapse: collapse; font-size: 13px; margin-top: 8px;
}
.ion-summary-table th { background: #f1f5f9; text-align: left; padding: 6px 10px; font-weight: 600; color: #475569; border-bottom: 1px solid #e2e8f0; }
.ion-summary-table td { padding: 5px 10px; border-bottom: 1px solid #f1f5f9; }
.ion-summary-footer { font-size: 14px; font-weight: 600; padding: 8px 10px; }
.ion-summary-footer.ok { color: #059669; }
.ion-summary-footer.error { color: #dc2626; }

/* ---- MD Stage Boxes ---- */
.md-stage-box {
  margin-top: 12px; padding: 14px 16px;
  border: 1px solid #e2e8f0; border-radius: 8px;
  background: #fafbfc;
}
.md-stage-box h4 { font-size: 14px; color: #475569; margin: 0 0 10px; }

/* ---- SimParams stage cards ---- */
.sim-stage-card {
  border: 1px solid #e2e8f0; border-radius: 8px; margin-bottom: 8px;
  background: #fff; overflow: hidden;
}
.sim-stage-header {
  display: flex; align-items: center; gap: 10px;
  background: #f8fafc; user-select: none;
  border-bottom: 1px solid transparent;
}
.sim-stage-toggle {
  display: flex; align-items: center; gap: 10px; flex: 1; min-width: 0;
  padding: 8px 14px; border: 0; background: transparent; color: inherit;
  font: inherit; text-align: left; cursor: pointer;
}
.sim-stage-header:hover { background: #f1f5f9; }
.sim-stage-toggle:focus-visible { outline: 3px solid rgba(37,99,235,.35); outline-offset: -3px; }
.sim-stage-header.open { border-bottom-color: #e2e8f0; }
.sim-stage-icon { font-size: 16px; width: 22px; text-align: center; }
.sim-stage-title { font-weight: 600; font-size: 13px; color: #1e293b; flex: 1; }
.sim-stage-summary { font-size: 11px; color: #64748b; text-align: right; line-height: 1.4; }
.sim-stage-header .stage-enabled { margin-left: auto; margin-right: 14px; flex: 0 0 auto; }
.sim-stage-body { display: none; padding: 10px 14px; }
.sim-stage-body.open { display: block; }
.sim-stage-body .param-row {
  display: flex; gap: 12px; flex-wrap: wrap; align-items: flex-end;
  margin-bottom: 8px; padding-bottom: 8px; border-bottom: 1px solid #f1f5f9;
}
.sim-stage-body .param-row:last-child { border-bottom: none; margin-bottom: 0; }
.sim-stage-body .param-item { flex: 0 0 auto; }
.sim-stage-body .param-item label,
.sim-stage-body .param-item .param-label { display: block; font-size: 11px; color: #64748b; margin-bottom: 2px; }
.sim-stage-body .param-item input,
.sim-stage-body .param-item select { padding: 4px 6px; font-size: 12px; border: 1px solid #cbd5e1; border-radius: 4px; }
.sim-stage-body .param-item input { width: 80px; }
.sim-stage-body .param-item input.wide { width: 100px; }
.sim-stage-body .param-item input.narrow { width: 60px; }
.sim-stage-body .param-textarea { margin-top: 8px; }
.sim-stage-body .param-textarea label { display: block; font-size: 11px; color: #475569; margin-bottom: 4px; font-weight: 600; }
.sim-stage-body .param-textarea textarea { width: 100%; box-sizing: border-box; padding: 7px 9px; border: 1px solid #cbd5e1; border-radius: 4px; font-family: monospace; font-size: 12px; resize: vertical; }
.sim-stage-body .param-textarea .hint { display: block; margin-top: 3px; }

/* Production iterations */
.prod-iter-row {
  display: flex; gap: 10px; align-items: center; padding: 6px 8px;
  background: #f8fafc; border: 1px solid #e2e8f0; border-radius: 5px; margin-bottom: 4px;
  font-size: 12px;
}
.prod-iter-row input { width: 90px; padding: 3px 5px; font-size: 12px; border: 1px solid #cbd5e1; border-radius: 3px; }
.ion-neutralize-pair { margin-top: 8px; padding: 10px 14px; background: #fefce8; border: 1px solid #fde68a; border-radius: 6px; }
.ion-neutralize-pair h4 { font-size: 13px; margin: 0 0 6px; color: #92400e; }
.ion-neutralize-pair.hidden { display: none; }
.ion-neutralize-pair select { padding: 3px 6px; font-size: 12px; border: 1px solid #cbd5e1; border-radius: 4px; }

/* Optional homepage announcements, supplied by a deployment extension.
   Absent in public builds, where the region renders nothing at all. */
.announcements {
  display: flex;
  flex-direction: column;
  gap: 10px;
  margin: 0 0 18px;
}

.announcement {
  border: 1px solid #d6dae1;
  border-left-width: 4px;
  border-radius: 6px;
  padding: 10px 14px;
  background: #fbfcfd;
}

.announcement h3 {
  margin: 0 0 4px;
  font-size: 15px;
  font-weight: 600;
}

.announcement p {
  margin: 0;
  font-size: 13px;
  line-height: 1.5;
  color: #444c56;
  white-space: pre-wrap;
}

.announcement-info { border-left-color: #2563eb; }
.announcement-notice { border-left-color: #0f9d58; }
.announcement-warning { border-left-color: #f59e0b; }

.announcement-critical { border-left-color: #dc2626; }

.announcement-pinned {
  background: #fff8ec;
  border-color: #f0d9b5;
}

.announcement-pin {
  color: #b45309;
  font-weight: 700;
  margin-right: 2px;
}

.announcement-link {
  margin: 6px 0 0;
  font-size: 13px;
}

.announcement-link a { color: #2563eb; }

.visually-hidden {
  position: absolute;
  width: 1px;
  height: 1px;
  margin: -1px;
  padding: 0;
  overflow: hidden;
  clip: rect(0 0 0 0);
  white-space: nowrap;
  border: 0;
}

/* Check progress: one bar per step, created under its own Check button.
   Blue and animated while the step runs, green and static once it is done. */
.step-progress {
  /* The bar is inserted after a Check button wherever that button lives, so
     it must claim a full row of whatever lays that panel out. */
  width: 100%;
  flex: 1 1 100%;
  grid-column: 1 / -1;
  margin: 10px 0 4px;
  padding: 10px 12px;
  border: 1px solid var(--border);
  border-radius: 6px;
  background: #f8fafc;
  transition: border-color 240ms ease, background-color 240ms ease;
}

.step-progress-row {
  display: flex;
  align-items: center;
  gap: 10px;
}

.step-progress-track {
  flex: 1;
  height: 8px;
  border-radius: 4px;
  background: #e2e8f0;
  overflow: hidden;
}

.step-progress-bar {
  height: 100%;
  width: 0;
  border-radius: 4px;
  background: var(--primary);
  transition: width 300ms ease, background-color 240ms ease;
}

.step-progress-percent {
  min-width: 38px;
  text-align: right;
  font-size: 12px;
  font-variant-numeric: tabular-nums;
  color: var(--primary-hover);
}

.step-progress-foot {
  display: flex;
  justify-content: space-between;
  align-items: baseline;
  gap: 12px;
  margin-top: 6px;
  font-size: 12px;
  color: var(--text-muted);
}

.step-progress-elapsed { font-variant-numeric: tabular-nums; white-space: nowrap; }

/* Running: the fill holds the position the server last reported, so the
   moving stripes -- not an invented percentage -- are what say the step is
   still working during a long phase. */
.step-progress[data-state="running"] { border-color: #bfdbfe; background: #f5f9ff; }
.step-progress[data-state="running"] .step-progress-bar {
  background-image: linear-gradient(
    115deg,
    rgba(255, 255, 255, .35) 25%, transparent 25%,
    transparent 50%, rgba(255, 255, 255, .35) 50%,
    rgba(255, 255, 255, .35) 75%, transparent 75%
  );
  background-size: 22px 22px;
  animation: step-progress-roll 800ms linear infinite;
}

@keyframes step-progress-roll {
  from { background-position: 0 0; }
  to { background-position: 22px 0; }
}

@media (prefers-reduced-motion: reduce) {
  .step-progress[data-state="running"] .step-progress-bar { animation: none; }
}

.step-progress[data-state="done"] { border-color: #86efac; background: #f0fdf4; }
.step-progress[data-state="done"] .step-progress-bar { background: var(--success); }
.step-progress[data-state="done"] .step-progress-percent { color: #15803d; }
.step-progress[data-state="done"] .step-progress-phase { color: #15803d; font-weight: 600; }

.step-progress[data-state="error"] { border-color: #fecaca; background: #fef2f2; }
.step-progress[data-state="error"] .step-progress-bar { background: var(--danger); }
.step-progress[data-state="error"] .step-progress-percent { color: #b91c1c; }
.step-progress[data-state="error"] .step-progress-phase { color: #b91c1c; font-weight: 600; }

/* Background ligand parameterization, reported on the Force Field panel. It
   is a note about work already under way, not a control, so it stays quiet. */
.ligand-prep {
  margin-top: 8px;
  font-size: 12px;
  color: var(--text-muted);
}

.ligand-prep[data-state="running"] { color: var(--primary-hover); }
.ligand-prep[data-state="done"] { color: #15803d; }